Benralizumab, a monoclonal antibody used for the treatment of severe eosinophilic asthma, continues to be a crucial biologic in respiratory care. Governments worldwide are increasingly investing in Benralizumab to improve asthma management and reduce hospitalizations. This report provides a detailed analysis of Benralizumab procurement in 2024, covering total government spending, top procuring countries, key buyers, and funding agencies.
Uses of Benralizumab
Benralizumab is primarily used for:
- Severe Eosinophilic Asthma – Lowers asthma attacks and reduces the need for steroids.
- Better Breathing – Helps control symptoms and prevent flare-ups.
- Eosinophil Reduction – Targets and removes cells that cause inflammation.
- Improved Lung Function – Helps lungs work better.
- Enhanced Daily Life – Reduces asthma-related struggles.
- Less Steroid Use – Lowers dependence on long-term steroids and their side effects.
Total Government Spending in 2024
Global government spending on Benralizumab reached approximately $1.5 billion in 2024, a 10% increase from the previous year. This growth reflects the rising adoption of biologic therapies for eosinophilic asthma, driven by several key factors:
Increased Adoption of Biologic Therapies
Benralizumab offers better disease control and fewer exacerbations than traditional treatments, leading to wider clinical adoption.
Expanded Government Healthcare Programs
More countries now include biologics in public healthcare plans, aiming to reduce asthma-related hospitalizations and emergency care costs.
Growing Awareness of Eosinophilic Asthma
Education initiatives and advocacy efforts have improved diagnosis rates, increasing the number of patients eligible for Benralizumab.
Top Procuring Countries
- United States – $600 million, driven by Medicare and Medicaid coverage, with rising demand due to an aging population.
- United Kingdom – $250 million, due to strong NHS procurement and government initiatives promoting early intervention.
- Germany – $200 million, with increasing use in public hospitals and expanded reimbursement policies.
- China – $180 million, supported by national insurance policies and rising asthma incidence due to urbanization.
- Japan – $120 million, reflecting a focus on advanced asthma care and growing investment in personalized treatments.
Top Procuring Regions
- North America – Leads in overall pharmaceutical API spending, reaching $700 million, driven by high demand and advanced healthcare infrastructure.
- Europe – Follows with $550 million, supported by strong government reimbursements and a well-established healthcare system.
- Asia-Pacific – Records $200 million, showing steady growth due to increasing healthcare investments and expanding pharmaceutical markets.
- Latin America & Africa – Account for $50 million, with improving accessibility and rising pharmaceutical demand.
Key Buyers
- U.S. Department of Health & Human Services (HHS) – Leads with $500 million in pharmaceutical purchases, reflecting its significant investment in public health initiatives.
- UK’s National Health Service (NHS) – Follows with $230 million, underscoring its commitment to providing essential medicines to millions.
- German Federal Joint Committee – Allocates $180 million, highlighting its role in regulating and funding healthcare services.
- Chinese National Healthcare Security Administration – Secures $150 million in pharmaceutical acquisitions, reinforcing its focus on accessible and affordable healthcare.
Funding Agencies
- World Health Organization (WHO) – Allocated $100 million to support access to asthma treatments in low-income countries.
- Global Asthma Fund – Dedicated $150 million to improve asthma care and accessibility worldwide.
- Public Health Insurance Programs – Cover 80% of asthma medication purchases, ensuring affordability for patients.
Trends in Benralizumab Procurement (2023 vs. 2024)
Bulk Purchasing Agreements
Bulk purchasing agreements have risen by 15%, driving cost efficiencies and improved access to essential medications.
National Reimbursement Programs
National reimbursement programs are expanding to cover biologics, ensuring broader patient access to advanced treatments.
Growing Awareness of Precision Medicine
Growing awareness of precision medicine is transforming asthma management, enabling more targeted and effective therapies.
Key Suppliers
- AstraZeneca’s Fasenra – Achieved $1.2 billion in global sales, solidifying its position in the asthma biologics market.
- Biosimilar Competition – Expected market entry by 2025, potentially driving pricing pressures and increasing competition.
- Sandoz (Novartis Division) – A major biosimilar player with a focus on monoclonal antibody therapies.
- Biocon Biologics – Developing biosimilars for a range of biologic therapies, including respiratory conditions.
- Pfizer – Has invested in biosimilars and could expand into the anti-IL-5Rα market.
Conclusion
Benralizumab continues to play a significant role in government-funded respiratory care programs. Increased spending, wider insurance coverage, and a growing emphasis on biologics for asthma treatment are driving procurement trends. With biosimilars on the horizon, cost reductions and expanded access are expected in the coming years.
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