Name: BIRAC ANNOUNCES REQUEST FOR PROPOSALS FOR UNDER NATIONAL BIOPHARMA MISSION LAST DATE :24TH APRIL, 2023 05:00 PM
Start: 2023-03-31
End: 2023-04-24
Location: BIOTECHNOLOGY INDUSTRY RESEARCH ASSISTANCE COUNCIL (BIRAC)

Organization Details:

Organization Name:

BIOTECHNOLOGY INDUSTRY RESEARCH ASSISTANCE COUNCIL (BIRAC)

Country:

India

Contact Person:

Address:

1st Floor ,
MTNL Building ,9 ,
CGO Complex,
Lodhi Road,
New Delhi-110003 ,

Contact Details - Email:

birac.dbt@nic.in

Phone

+91-11-24389600

Notice Details:

Notice Type

Tender Notice

Bidding Type

Other

Notice No.

64179244

Deadline

2023-04-24

Description

BIRAC ANNOUNCES REQUEST FOR PROPOSALS FOR UNDER NATIONAL
BIOPHARMA MISSION LAST DATE :24TH APRIL, 2023 05:00 PM
INTRODUCTION
Program Overview - NBM

This is an Industry-Academia Collaborative Mission for
Accelerating Discovery Research to Early Development for
Biopharmaceuticals - “Innovate
in India (i3) Empowering biotech entrepreneurs &
accelerating inclusive innovation”, also referred
to as National Biopharma Mission (NBM).

Funding agency

Department of Biotechnology (DBT) (Program co-funded by
World Bank loan)

Implementing agency

Biotechnology Industry Research Assistance Council
(BIRAC)
KEY FEATURES OF THE CALL
This program is to seek Request
for Proposals (RFP) for supporting – Development
of products active against sensitive
and drug resistant microbial
pathogens mentioned in the Indian Priority
Pathogen list (mainly, E. coli, Klebsiella
Pneumoniae, Acinetobacter baumanii, Pseudomonas
aeruginosa, Staphylococcus aureus, carbapenem resistant
Enterobacteriaceae (CRE). The products should have
established proof of principle including
but not limited to the
following -:
New Chemical Entities or antibiotics from a
new class with a novel
mechanism of action (first in class), or
pre-existing class of drugs (best in
class), Repurposed Drugs, Combination with existing
drugs
Therapeutics which may be broad-spectrum
or pathogen-specific antimicrobial
Peptides, genetically-engineered antibodies,
Immunomodulators, molecules that
modulate virulence or pathogenicity, Microbiome
modulating agents, bacteriophage therapies
Scope of the Call:
a) The diagnostic should have demonstrated proof
of concept (Completed TRL-3* stage as per BIRAC TRL
definitions - https://www.birac.nic.in/desc_new.php?id=44)
b) The diagnostic should detect at
least one and preferably two of the critical bacterial
pathogens as prioritized in the Indian Priority
Pathogen List developed by WHO India and
the Department of Biotechnology, Govt. of India, and/or
test their susceptibility
profiles3
c) The areas of support may include validation
of prototypes or production
technologies; adaptation of products or platform
technologies to new applications; manufacturing and scale-up for
deployment
d) The diagnostic should fulfil at
least one or more of the following criteria:

1) Rapid
detection test (with test
time of <4 hours) that differentially
detect and identify species
2) Culture-independent and should focus
on direct detection of the target pathogen(s) from
primary samples
3) Point-of-Care Tests/kits (POCT) that
can be manufactured at large scale
WHO CAN APPLY?
The proposals can be submitted:
a) Solely by Indian Company / LLP/ Non-profit
organizations/ Society/ Trusts/ Foundation/Associations/
Government entities/ Institutes/ R&D Organizations/
which is a legal entity OR
b) Jointly by Indian Companies/ Non-profit organizations
/ LLP/ Society/ Trusts/ Foundation/Associations/
Government entities/ Institutes/ R&D Organizations/ OR
c) By an Industry-academia consortium
of Indian Company/ Non-profit organizations/
LLP/Society/ Trusts/ Foundation/ Association/ Government entities/ Institutes/ R&D
Organizations
a) Indian Start-up companies in collaboration with
Industry/Academia/research institutes/ are specia

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